For years I’ve been bothered with urgency and frequency issues. These have got worse over time.
I’ve been prescribed every drug known to mankind to try and deal with this. Until recently, the only ones that were any way effective also resulted in hideous constipation.
Recently, my patient GP prescribed mirabegron which worked reasonably well. As an experiment, he also prescribed toltolderone to work alongside the mirabegron. No good. The constipation returned. He then prescribed oxybutylin to work along side the Mirabegron. This. Combination is working great. Reasonable bladder control without the constipation.
I’ve gone from peeing 5 or 6 times during he night to 2 or 3 times a night. What a difference. The urgency has calmed somewhat.
i think I have tried everything before in isolation, but it was only recently that the GP suggested a mix of two bladder treatments. And it was only through perseverence that we hit on the right combination for me.