Switching from Tysabri

Hi,

I have been having Tysabri infusions for 10 years but have just tested JC positive and have to stop. I was just wondering if anyone could tell me which treatments they were offered if this happened to them?

Thank you

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I am very sorry to hear this. That’s very disappointing for you.

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Hi
Have you now been offered a new dmt ?
Due my first tysabri in two weeks one of my questions will be what options I have if I turn jcv positive
I’ve seen mavenclad mention on another forum

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I was offered Kesimpta or Ocrevus and I opted for Kesimpta. I hope Tysabri works well for you :slight_smile:

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Thanks
Glad to hear you’re all sorted for a new dmt , if I was allowed anti cd20 I think kesimpta would be my choice also

Hi
had my first tysabri injection today I did ask about what would happen if I became jcv positive and was told I would still be possibly kept on it for a while as long as the numbers were relatively low
we didn’t really get to what the choices would be if had to change more of a we will see at the time
Wasn’t expecting the infection either but going forward that’s what I’ll be receiving every 4weeks :crossed_fingers:

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You can use the Barts Guide to calculate your risk.

Understand your risk of PML with Natalizumab

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