LDN: liquid or tablets?

Hi everyone I just have a general question re: LDN I have been taking the liquid form of LDN for approx. 5 years. I am now relapsing remitting secondary progressive (was dx. RR 13 yrs ago). I am not currently on any medication apart from LDN. I really don’t know if I should continue LDN or stop taking it or try the tablets now because I may have become immune to the effects of the liquid form. Is that possible? Apart from the obvious (liquid vs solid) is there any difference/better effect by taking it in tablet form? This is probably a stupid question but does anyone have any thoughts on this? Thanks Tracy

In my experience there is no difference, but some say liquid ldn gets into the system quicker. The only thing I can say is that there will be no harm in trying. Alternatively, you could try taking a break for a short while and see if there is any change.

Not a stupid question at all and wish I had a solution.

l had a break from LDN - only because l ran out and l had trouble with my lap-top when l needed to re-order my emed prescriptions. Symptoms did start returning - and once again back on ldn - even after the first day - l feel much better.

l always took the liquid - which l never liked - but l am on the capsules now - they are more costly - and you can not juggle the dose - its 3ml or 4.5. But so glad to be back on them.

I don’t know what dose you take, but it could be worth reducing the amount and see if it helps. According to Dr Zagon it is possible for long term ldners to accumulate the drug in the system and this can cause difficulties.

Sadly, I have no idea if this is true, but can’t do any harm to try.

“However, when you take LDN over extended periods, some Naltrexone will accumulate in the system and this can become troublesome. It can perhaps even prevent LDN from working well. It seems a blockade lasting longer than about 6 hours may stop the LDN working and can even make it work in the opposite direction. This can be remedied by skipping a day – even two days in extreme cases but no more than that! This will help reduce the accumulated level of naltrexone. Much research is needed here and naltrexone residual level monitoring equipment would help too.”

My doctor has changed me from tablet to liquid because the tablets were the most expensive drug he was prescribing and the practice manager told him it would have to change. Any one else in same position?