Please could anyone advise. I started the low dose of tecfidera on Tuesday evening, so have had 5 tablets. I have experienced flushing, although can live with that. But 24 hours after I started taking the meds I have this strange feeling in my arms and legs, particularly when I lie down and try to sleep. It’s not pain as such but it is making me need to shift position every few minutes, making sleep practically impossible. It’s like an unbearable restlessness. May be coincidence, I’ve looked at the leaflet and doesn’t mention anything like that but I know the professionals are still learning about this drug. Has anyone else experienced anything similar? It’s driving me nuts. Thanks.