Well, something like 80-95% of people with MS have Oligoclonal bands in their CSF (cerebrospinal fluid), but not in their blood serum, so I’d have expected the letter to say something about blood serum, but regardless, you do have O bands in CSF.
I think the bits about altered signal would be lesions of one type or another. Their specific place within the brain is important, but I’m lacking the knowledge to explain anything about that. The first bit of altered signal shows no enhancement so there’s no disease activity. And the second has enhancement showing active demyelination.
I reckon the doctor has pretty much diagnosed you already (I looked back at the post where he said you had ‘mild MS’. Therefore the MRI was backing up what he’d already thought. In particular, the active demyelination on the second area of altered signal probably means an active lesion, to my mind putting you in the relapsing remitting type of MS. The reason I think this is because my last letter about a recent MRI said there were 2 small enhancing lesions so in spite of having been diagnosed SP, my MS has become active again and therefore is Progressive Relapsing.
Obviously you could read through Rizzos post on how to demystify your MRI report at the top of this page, but it’s long and fairly technical. Or just wait for the appointment. Although I think you and I know what will be said at that appointment.
Your next challenge will be (hopefully) to think about which DMDs you would prefer to take. I assume you would a) be offered them, and b) decide the risks of side affects are worth the benefits in terms of relapse reduction.
You won’t have a completely free choice, but it’s worth knowing what the various options might be. You’ve probably already seen this, but have a look at https://www.mstrust.org.uk/about-ms/ms-treatments/ms-decisions-aid
At least it’s not too long until your appointment.