All good answers.
I have 3 relatively small lesions in the upper half of my spine and it affects my mobility, a lot some days, also the sensation in my hands and bladder issues.
I’ve even progressed to SPMS without showing any more lesions, the damage that the existing 3 have done is just getting worse !
My sister has a good number of lesions in the whole of the spine and her symptoms were about the same as mine, however 6 months ago she had a relapse and a lesion appeared in the brain stem, totally life changing, it has affected everything, from walking, talking, eating, concentration, bladder & bowel issues, so just one extra lesion in the wrong spot and a totally different outcome.
My cousin has no lesions in the spine what so ever, but many scattered throughout the brain, her mobility is hardly affected, she has issues with gripping things, her vision is affected when she’s having a bad day, and also has a lot of muscle & joint pain.
On a good day you would never think she had MS, yet as far as the number of lesions, she’s in the premier league !
So I think the point is, it doesnt matter on the number of lesions, its where the little b*stards appear is the problem.