Reading your post - l could recognise how l was up till 6yrs ago. Fatigue/pain/depression etc. Then several peeps on here told me about LDN - and l started taking it. Now l know it does not seem to suit everyone - but for me it was life changing. ln fact its one of the things people comment about me - how positive l am. l know its not a cure - but it certainly makes life easier - and l find l cope so much better. Far less fatigue - and for most it helps with bladder control. l just wish l had known about it years ago. Recently, a friend of mine has started taking it - she wasn’t very hopeful - then she surprised herself when she found she had walked a favourite route that she had not managed for a long time. Now she finds she is tired - because she has done so much during the day.
l feel very upbeat on LDN - also a high dose vitd3/magnesium/b12 l hate taking any meds that make me drowsy - foggy brain. OK, l still cannot walk unaided - but you would be amazed at how much l can manage to do. And l rarely sit down all day - just hang on to my rollator!! And use my Tramper to get out with the dogs - now that is sitting down - but the rough ground l go over bumps me about and l need to brace myself to stay in control - so this must be also working muscles.
l am now 67 - and l have had ~PPMS for 32yrs.