I have been on Tysabri for a little over a year now (previously on REBIF). I am JC+, but I didnt find that out until my third infusion.
The facts and figures surrounding the JC virus and Tysabri can be daunting - but for me personally the possible positives of it far outweighed them. On REBIF I constantly relapsed and the side effects from the drug for me were just awful. Since starting Ty I have had no relapses at all and also no side effects. The first few infusions I felt quite head achey and tired for a few days afterwards - but nothing major at all. At first there were no major differences in how I felt, but now I feel my walking is better and also the fatuigue is better. They say it wont help anything like that - but I believe it does.
Do you know where you will be treated? I am in Southampton and the nurses there keep a close eye on everyone but more so if you are JC +. All the people in my group are JC+. 90% of the time its the same nurses so they know you well and can easily pick up on anything that may be nasty. We also get annual MRI’s (some hospitals do more frequent ones for the JC+ people) and to be honest I couldnt ask for better care and I also would not give Ty up if you paid me!!
It all comes down to what is best for you. Before I started my nurse told me to make myself aware of the risks if I were JC+ but also not to dwell too much on it.
If you want anymore info from me (I no medical guru - but as a person on Ty and JC+) just PM or on here. whatever.
Good luck xxxxxxxxx