I am on week two of tecfidera.
Week one with 120mg each morning was no trouble at all
Week two with one in the morning and one in the evening is proving a little uncomfortable; two days of stomach cramps and two incidences of (ahem) ‘Dehli belly’.
The squits however, were short lived and could be attributable to a nuclear hot curry eaten with a few bevvies the day or so before… ie. far from being clinically proven to be a tecfidera side effect. Also, they were not ‘urgent’ so even the slow of foot would be okay.
The cramps were easily inhibited by the use of aspirin, which is indeed recommended to reduce flushing.
I have small anxiety when considering i am only up to 50% dosing right now, due to start on 75% dosing tomorrow. But i am not about to jab myself daily, nor succumb to this bull5hit called MS and so…
Long story short - tecfidera is the best out there right now for RRMS. Everyone’s reaction to it will be different. For me, the side effects have been mild, short lived and easily managed.
Best advice thus far: take on full stomach NOT on empty food or with just a light snack; take an aspirin 30 minutes before.