Hi - I posted this thread on the PPMS forum but was recommended to post it here as well !
My husband has PPMS (diagnosed 4 years ago) and was selected to take part in a 2 year stem cell trial based in Bristol. Last year following a battery of rather unpleasant tests, he had stem cells harvested and then had an infusion put back into him. He doesn’t know whether he had stem cells or a placebo but is now awaiting to have whatever he didn’t have last year infused. Is anyone else involved in this trial or a similar one ? We re wondering what their experiences have been - so far he believes he only had the placebo as his symptoms have worsened but he wants to stay optimistic that next year things may be more positive.
What type of stem cells did the trial involve? Where were they taken from (blood, bone marrow or fat cells) and where were they put back (into the blood or into the CSF).
i am SP,M/S m/s dx20yrs,sp 2yrs oh joy not, went too nuero last week MANCHESTER & he offered me a ( new drug ) in three month time as all other meds js made me crazy/mad/horrid, new med’s 2yrs course 3 mounth check ups js waiting for start date!! that’s all i know at the moment, but was js so elated +my sis i will keep yall up 2spreed
julien
It doesn’t involve chemotherapy - the trial is being run by Actimus at Bristol University under Prof Scolding. He had bone marrow taken from his pelvic area and 500ml of blood taken. Last year he either had bone marrow or blood infused back into a peripheral vein. If he didn’t receive bone marrow it was frozen and he will have it infused later this year. The title on the information sheet he was given was “assessment of Bone Marrow-derived cellular therapy in MS” and the purpose of the study “is to test the safety of bone marrow stem cell infusions” An earlier safety trial raised the possibility of partial repair, measurements of the speed and neurological impulses in the brain and spine improved so the trial he is on will test the validity of those results and maybe improve therapy for the future.