Ocrevus side effect - strange groggy feeling

Symptoms and treatments
1

Hi guys,

Had my first Ocrevus treatment 1m ago. Been generally fine, was tired after the treatment but not noticed any major side effects. One thing that is bugging me a little is this strange feeling of pretty constantly feeling like I’m about to come down with something. It’s so hard to describe but the best way I can is to compare it to the feeling you have when you’ve been sat in the sun for too long. Except I just get it sat on the sofa or sat at my desk working. It’s kind of a groggy feeling. Thought it could be hay fever so took anti histamines for a few days but no change. I’ve tried googling and nothing comes up but I don’t know if I’m describing it how others would?? I’ve never felt this exact feeling before but I’ve had it pretty consistently since the Ocrevus treatment. Maybe it’s just my immune system figuring things out? I’m not sure but would be interesting to know if anyone else has felt this way…

2

Hi Ssaf,

I’ve had similar, as it deletes half your immune system you will be susceptible to infections. I tend to always have “something” I still want to keep having it though. Don’t know if you have kids but I call my young Daughter patient 0 these days. :joy:

Separately, noting I’m not in anyway a medical professional (at all) there has been some studies which indicated certain antihistamines may be detrimental for MS progression (please do not take that as advice, I’m not certain it has been confirmed and it will maybe be specific ones, talk to a professional).

I’d say if you have an MS nurse talk to them, there is also the hotline on here. Since it’s your first time it might be good just to talk it out. We are all in a way finding out and aren’t professionals so researching is just another thing to the fun of having MS. It’s easy to go into stress/research spiral and be ill.

Cheers,
Andrew