Hi everyone,
I am desperate for some advice on switching to a new MS drug. I was on Kesimpta since March 2025 and have had a heap of chest infections plus hair loss that has thankfully stopped since August when I stopped taking Kesimpta. I was in Brabio before and as much as I would prefer to go back to that, I don’t think my neurologist will agree. I have explored Tysabri and Tecfidera but am unsure about both. Does anyone have any experiences of those medicines?
Hi
I am on Tyruko, (tysabri) and I find it no problem at all. I was diagnosed in Sept/Oct 24 and started treatment in early October 24.
Morag
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I have been on natalizumab (Tysabri and now Tyruko) for well over ten years. It has been a wonder drug for me and stopped my active RRMS in its tracks.
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Thanks. That’s really helpful. Its a drug I am considering alongside Tecfidera. I just have to wait and see what my Neurologist says about it.
That’s amazing! I’m so glad its stopped the activity for you. 
Thank you. So am I. 
The heavy-hitter drugs really can do that.
Hi, I’m currently on Tecfidera and have found the medication no problem at all, very little side effects and easy to take. However it has not stopped me getting multiple new lesions and I am now being offered the next stage of treatment including Kesimpta. I imagine you’ve spoke to your Neurologist now but I think Tecfidera is less effective so may not be the best option in your case…