lumbar puncture

Can strong co-codamol affect lumbar . Will it reduce the inflammation results.

Hi Nanny Julie,

No, if there was any medication that would affect the results, you would be warned in advance of the test not to take it.

Codeine and paracetamol (the ingredients of co-codamol) aren’t anti-inflammatories. Paracetamol is considered to have a very mild anti-inflammatory effect, but not enough to be classed as an anti-inflammatory.

Besides, it’s a different kind of inflammation anyway - if CNS inflammation could be controlled by co-codamol, or ibuprofen, or whatever, we’d all just take those, and MS wouldn’t be a problem. The test actually looks for proteins that are a tell-tale sign of myelin destruction, so it doesn’t test for inflammation in a direct way - it can just tell if there has been some by the resulting debris. So no painkillers you are on will have any effect whatsoever.

Hope this helps,


Thank you very much tina . Yes you explained it really well. I was at neurons and they spoke alot about inflammation in brain and i wasn’t sure. Thank you so much. As finally feel like doctors are listening and i want an answer one way or another if possible x