If you have a washout period between tysabri and gilenya, you are more likely to have a relapse

Everyday living
1

Here’s a link to a paper showing that if you have a washout period between tysabri and gilenya, you are more likely to have a relapse. Not much of a surprise there, but I’m sure of interest to people who are going from one drug to the other. Personally, I will fight to stay on tysabri, when the time comes, no matter how high my JC virus levels get. But if I lose the fight, I won’t have a washout period. Here’s the link:

http://multiple-sclerosis-research.blogspot.com/2015/06/clinicspeak-did-we-need-trial-lasting-4.html

2

I’m in a washout period between Tysabri and Lemtrada, and I relapsed again very quickly, just 3.5 months since the last one.

My MS nurse is now telling me that she’s getting conflicting info about how long the washout period should be. She told me 3 months initially, now she’s heard from elsewhere that it should be 6, which is why she’s putting me on Tecfidera in the meantime.

Damn, I want to read that article properly, but the combination of lots of big ol’ medical terms and names, and big unwieldy paragraphs is making my brain switch off.

3

It’s another benefit of Tecfidera… it has a very VERY brief residence time.

Apparently it can be expelled from the body in a matter of hours!

This is of great use to those transitioning to another DMD, or for someone who finds the side effects of Tecfidera are intolerable (not that that happens very often either).

4

Yep! That’s why MS nursey’s keen to get me on it. I guess I’ll take my last doses of it the day before I start the Lemtrada!