Ocrevus (ocrelizumab) has passed phase 3 trials and is being fast-tracked by the FDA (US authority), it’s supposed to be approved on 27th December this year - it then has to be approved by the EMA (European authority, but apparently they usually follow the FDA’s lead), then has to pass the NICE criteria. But it’s not a myth or a dream, it is a reality, and I discussed it with my MS nurse last month.
Perhaps you’ll believe the Barts blog: Multiple Sclerosis Research: ResearchSpeak: ECTRIMS highlight ocrelizumab NEDA data - or even this forum - https://www.mssociety.org.uk/ms-research/treatments-in-the-pipeline/ocrelizumab.
It’s not a cure, it slows or halts progression. And that’s good enough for me, that will give me some hope. Because, quite honestly, hope is the only thing that keeps me going most days, and it’s in pretty short supply. But NICE won’t approve it if we all seem to not be bothered, will they?
The other DMT is Siponimod, but that’s not as far along the approval path (https://www.mssociety.org.uk/ms-research/treatments-in-the-pipeline/siponimod#avail).
I know these drugs are not without side effects and potentially very serious ones, I am very aware of that. But five and a half years ago I was on holiday in Lisbon like a “normal” person, and now I’m EDSS 6.5 - I spend a lot of my life watching my mobility, independence and dignity disappear down the toilet, and I’m asking myself, how much longer am I even going to have the limited mobility I have now and what price will I pay to retain what I have - and that is quite a high price, as I don’t relish the prospect of life in a wheelchair contemplating might-have-beens.
And I really sympathise where it’s come too late for people on this forum, I really do, I wish you could have it too, I wish it had been discovered/trialled years ago so none of us would be where we are now, but unfortunately it wasn’t.
If it turns out to have been a false hope - I think I’m paraphrasing Dr Jelinek - better false hope than no hope at all.