I was taking Avonex for about six years. I still think it was the best choice as it allowed me freedom from any flu symptoms during my working week - I always took it on Friday evenings. During the time I was taking it there were a few changes which made it much easier for me - a shorter needle and greater time without need for refridgeration (very handy for going on holiday).
But with this came the fact that I discovered an almost phobic fear of that long needle. By the time the shorter one was introduced I was getting used to necking a bottle of wine each Friday evening just to find the courage to jab myself with it. In reality it was never so bad but I had a game trying to get used to it. I used to inject into my leg but started to think the needle might come out of the other side (of course it didn’t!). Latterly I injected into my stomach as there is much less fine sensation there. Years later someone told me it wasn’t supposed to be injected into the stomach but I can’t remember why.
I hope you have an easier time with it. The problems I had were because of me - you won’t have the same experiences I’m sure, especially if you don’t mind injecting. If you take some Ibuprofen or Paracetamol it greatly helps with the flu symptoms. I used to take the Avonex late at night then take a couple of Ibuprofen tablets, then go to bed. I don’t think you will feel so poorly in the morning - I just felt a bit flu like first thing but it soon went and may have been as much to do with after effects of the wine. This was how I found it anyway.
Wishing you good luck with it.