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anyone used the amino acid gaba

have been advised to try gaba for stiffness, anyone tried it

HI joyj,I have never heard of this ,Just googled it and it sounds interesting. It will be interesting if anyone is on this. Let me know how you get on please. Take Care, Chris.

l just googled it too Chris - so l have ordered it from amazon 100caps of 750mg - lt is supposed to also help with sleep - as someone who rarely sleeps more than 3hrs a night -l will try anything.

Hi, not tried, but have read up about it. GABA is a nerotransmitter ocurring naturally in the body. It has a role in dampening down CNS excitability and regulating muscle tone. So, in theory at least, supplements might do something. BUT, I also uncovered in my reading that most over-the-counter formulations are unable to cross to blood-brain barrier, so they could never get into the CNS to do the job they are supposedly intended for. Also, Baclofen (the usual firstline prescription treatment for MS-related spasticity) is a derivative of GABA, and definitely CAN act on the CNS. So, if you’re attracted to the idea behind GABA, but want to try something that’s been scientifically proved to work, you might as well go straight for Baclofen, in my opinion. The fact something’s available “over-the-counter” doesn’t necessarily make it safer or more natural than going for the prescription stuff. And at least you know the prescription stuff actually does something. Which might not be true of supplements - especially if they’re in a form that goes straight through you without ever reaching the CNS! Tina

Anitra wrote:

Hi, not tried, but have read up about it. GABA is a nerotransmitter ocurring naturally in the body. It has a role in dampening down CNS excitability and regulating muscle tone. So, in theory at least, supplements might do something. BUT, I also uncovered in my reading that most over-the-counter formulations are unable to cross to blood-brain barrier, so they could never get into the CNS to do the job they are supposedly intended for. Also, Baclofen (the usual firstline prescription treatment for MS-related spasticity) is a derivative of GABA, and definitely CAN act on the CNS. So, if you’re attracted to the idea behind GABA, but want to try something that’s been scientifically proved to work, you might as well go straight for Baclofen, in my opinion. The fact something’s available “over-the-counter” doesn’t necessarily make it safer or more natural than going for the prescription stuff. And at least you know the prescription stuff actually does something. Which might not be true of supplements - especially if they’re in a form that goes straight through you without ever reaching the CNS! Tina

Hi Tina. Thanks for your input,already on baclofen,just started using Satovex,so will put that on the back boiler for a while,and give them time to see what happens. Take Care . Chris

gaba is natural, the others are synthetic. iv just had to change my blood pressure tablet to use it. the doctor giving it to me takes it himself for ms and has taken it over 20 yearsso thats a great reason for me. il keep you informed

joyj wrote:

gaba is natural, the others are synthetic. iv just had to change my blood pressure tablet to use it. the doctor giving it to me takes it himself for ms and has taken it over 20 yearsso thats a great reason for me. il keep you informed

Thanks Joy - lf its good enough for your doctor then l can’t wait to try it. Not that l would wish MS on anyone - but we could do with a lot more GP/Neuros with it - just so that they understand our problems.