I was diagnosed with relapsing-remitting MS about 2 years ago, and have been on monthly Tysabri infusions for the last 18 months. I’m really pleased with how it’s helped me as I’ve had no relapses since beginning treatment.
Since around last Christmas I’ve been very run down - constant colds/coughs/sore throats; sores and mouth ulcers; feeling like I have a virus all the time. Almost having as negative an effect on my life as untreated MS as it’s so constant! Blood tests haven’t turned anything up and my consultant says he thinks it’s probably because my immune system is overloaded (I also have very long standing type 1 diabetes and asthma but have never experienced anything like this before). He doesn’t think the Tysabri can have anything to do with it due to the way it targets certain parts of the immune system.
However, through reading forums and MS info sites, I’m finding that there are a significant number of people who do attribute their weakened immune systems to Tysabri and have been put on longer infusion schedules - waiting 6/8 weeks beween doses rather than 4, for example. This is not something my consultant will let me do at the moment. I’m wondering if anyone else has had similar experiences, or have been put on longer infusion schedules? While my consultant may very well be right, I’d like to try anything that might help the situation.
Thanks in advance!