I wanted to let everyone know about some very exciting research for older people with MS and the improvements I have seen since starting on the drugs being researched (Metformin and Clemastine).
The MS Society organised the lecture which is shown here Watch: Stop MS - Research Lecture 2018 - Professor Robin Franklin - YouTube as part of their Stop MS Campaign (the important bit is after 33:33 but it’s harder to understand if you don’t watch from the beginning). After I watched it, I asked my neurologist if I could start on Metformin and Clemastine. He was actually at the lecture and he agreed.
I’ve only been on the drugs for two weeks but in the last few days, I’ve been able to walk upstairs again (had only done that very occasionally in the last three months. I can get my own legs into bed. I’m walking with a frame first thing in the morning, rather than using a wheelchair.
To plenty of you, these may sound very small improvements. But they are making a huge difference to me. Even bigger for me is the fact that my walking is getting better, rather than worse - that hasn’t happened for years (in the past there’s pretty much been a slower or faster decline in my walking). That’s what is making me think that this is an effect of the Metformin and Clemastine.
I don’t know if anyone else watched this lecture and asked for these (very common, very cheap) drugs. I’m on 1,000 mg a day of Metformin and 8mg a day of Clemastine. These are high doses but I’m not seeing much in the way of side effects (may be sleeping a bit more because of the Clemastine).
Is anyone else trying this and what do people think?