Oral treatment for RRMS. Heve been reading about the ramdomised trial in NEMJ journal on oral teriflunomide for RRMS. I’m not sure it difficult to know if to stick with what is available currently or not.
Hi Helebon,
It’s passed the trials and is licenced as an alternative first line treatment to the standard injectables, from this week: http://www.mssociety.org.uk/ms-news/2014/01/new-ms-pill-nhs Or is that what you meant?
Have you been offered it? It remains to be seen how many neuros routinely offer it, and how many prefer to stick with the old tried-and-tested.
Reading more detailed reports, it seemed it had a lower drop-out rate than the interferons (but that might reflect people who simply don’t get on with injecting, rather than side-effects being milder), but was marginally less successful at preventing relapses.
I believe surveys have shown more than 90% of people who currently inject would prefer an oral DMD, if it was available, so I expect demand will be very high. I’m guessing that means not everyone who is interested or eligible will be offered it - especially at first.
Tina
Having RRMS oral treatment would be my choice without a doubt. I was lucky enough to be dx without a lumber puncture as my mri had enough change which was a big relief as i hate needles. Plus seeing my mom who also has MS inject 3 times a week and seeing all of her site marks puts me off. She wishes she could change to the oral treatment but as she is unsure if she is RR or SP (shes never been told) shes doesnt think she can x
My nurse said they will only change those on injectables to the oral one if they are having problems on the injectables as if not there is no need to change esp as there is no guarantee the oral one will agree with everyone. Like injectables don’t agree with everyone so they change. I would love am oral med however as annoying as the injections are some of me thinks if this is working at the moment then is it worth changing to one that I might not get on as well with. I have had some site reations which have eased now but she did say if they started again oral may then be offered. She also said there is another oral med coming out which has better results and once this is approved they would much rather offer this. Not sure what its called but cuts relapses by 50% Xxx
My nurse said they will only change those on injectables to the oral one if they are having problems on the injectables as if not there is no need to change esp as there is no guarantee the oral one will agree with everyone. Like injectables don’t agree with everyone so they change. I would love am oral med however as annoying as the injections are some of me thinks if this is working at the moment then is it worth changing to one that I might not get on as well with. I have had some site reations which have eased now but she did say if they started again oral may then be offered. She also said there is another oral med coming out which has better results and once this is approved they would much rather offer this. Not sure what its called but cuts relapses by 50% Xxx
i think cost will come into it. if the oral drug is cheaper the powers at b will push the new drug forwad. money money money.
im on copaxone and it seems to be doing its job for me. if i was offerd the new one i would decline. injecting every day dosnt bother me at all but i can understand that others dont like it.
Thanks for those replies. I have been offeedd DMD’s but thats an injection, am seeing an MS specialist in next few months, so not sure what he will say. I read somewhere these oral tablets offer a 6% reduction on average in disability over two years. And on that you there can be side effects. 6% reduction over two years, i’m on the fence. I know there could be the possibility it may be greater or less reduction than that for me.