Extended Prolonged Fasting Success

In 2022 a friend of mine recommended that I try fasting because I had become bedridden over the Christmas holidays of 2021. Diagnosed in 2018.

I did some research and found the study referenced on this website regarding every other day fasting for mice. But I looked a little deeper and mice and rats have a metabolism approximately three to five times faster than humans generally speaking.

This means that fasting a mouse or a rat for a day is like a human fasting for 3 to 5 days. Obviously I wasn’t prepared to fast for 120 hours but I could fast for 48 and 72 hours.

Ocrevus did not work for me and caused low total white blood cell count of 1,400. My last infusion was January of 2021.

I started fasting around March 1st and by July I was walking unassisted.

I usually fast 48 to 72 hours. No food, water and black coffee only once every week. Sometimes I miss a week. Sometimes I miss more than a week. But when I’m consistent I have almost no symptoms. The nystagmus, horizontal and vertical went away, There was a significant and continuing reduction in generalized pain. Fatigue has been greatly reduced.

If I miss more than 3 weeks then symptoms come back. I’ve done some research and fasting induces the deepest autophagy in the human brain of anything, any drug. Autophagy cleans out malfunctioning cells, reduces microglia inflammation and allows for oligodendrocyte differentiation and remyelination. Fasting reduces activation of the nlrp3 inflammasome, production of interleukin 6. Interleukin 23. Interleukin-17 and down regulates the activity of TH17 cells which are implicated in the pathogenesis of multiple sclerosis.

I’m happy to share My success story with anybody that has any questions.

Obviously everybody’s different with Ms but the basic underlying physiological pathways for inflammation and demyelination are consistent across everyone that has Ms and fasting disrupt that process and allows for the body to start healing.

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Hi @karlerik.heuer Thank you for your post. Good and interesting to hear that it’s working for you. I’ve done time restricted fasting - eating only during a restricted number of hours each day. I was doing 8 hours, sometimes getting down to six but that all went out of the window this year. My wife developed cancer and has been going through more or less a year of surgery and treatment and I rather forgot about fasting.

Can I ask how did you manage with such long fasts, how did you find it and do you have tips.? I’m fine during the day but find I hard to sleep on an empty stomach.