You and I both seem to have a rough time on Avonex Pat but we are a very rare breed indeed. Far more people report a positive experience and successfully manage their MS and reduce the number of relapses by using Avonex or other DMDs than suffer allergic or adverse reactions to them.
Seizures from Avonex is a very rare side effect indeed and not one that most people need to be concerned about. In the clinical trials only 4 people developed seizures and of those 4 one already had a pre-existing seizure disorder anyway. Seizures also do occur in MS as part of the disease so it is hard to know if the seizures in the trials were directly attributable to Avonex or to the MS.
The following is a few exerpts from a quick Google search on Avonex seizures as suggested by Pat.
Avonex should be used with caution in individuals with a seizure disorder. A few individuals with no prior history of seizures have experienced seizures while on Avonex. Since seizures are known to occur somewhat more frequently in people with MS than in the general population, it is not known whether these seizures were related to the MS, to the medication, or to some combination of the two.
Caution should be exercised when administering AVONEX® to patients with pre-existing seizure disorders. In the two placebo-controlled studies in multiple sclerosis, 4 patients receiving AVONEX® experienced seizures, while no seizures occurred in the placebo group. Three of these 4 patients had no prior history of seizure (see ADVERSE REACTIONS). It is not known whether these events were related to the effects of multiple sclerosis alone, to AVONEX®, or to a combination of both. The effect of AVONEX® administration on the medical management of patients with seizure disorder is unknown.
Get medical help right away if any of these rare but very serious side effects occur: chest pain, seizures.
A very serious allergic reaction to this drug is unlikely, but get medical help right away if it occurs. Symptoms of a serious allergic reaction may include: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.
Like all drugs Avonex does have side effects. I am also one who cannot take it due to a severe allergic reaction. I developed hives and swelling of the mouth and throat with both Betaferon and Avonex. My neuro decided not to bother trying Rebif! But this is really, really rare. I would never suggest that this is the norm and I would never suggest that another person may also have a bad experience based on mine. When you consider the many, many thousands of people who take Avonex very successfully I think it is terribly important to put my experience and Pat’s into perspective and to recognize that we are the exception and were very unlucky.
All the best with starting it, Podium