Whatever you ask about on here, you will usually hear from the people who have had good experiences rather than bad ones. Just for balance, I was on LDN for something near to two years, I think, could have been longer. My (useless) neuro was happy to give me a private prescription, as long as I found out everything about dosage, where to get it etc. I went along happily enough on it for a while, then started to have relapses. I had been diagnosed with MS for about seven years at this stage, had only had one relapse, after which I was diagnosed. About a year and a half of taking the LDN, I had a disabling relapse, another a year later, then started to go to two a year, then three. I think I stopped taking the LDN between my second and third (ever) relapses but it could have been between the third and fourth. I didn’t feel it did anything for me at all.