I was on the phase 3 Tysabri trial from April 2002 and since a Tysabri patient. I have been relapse free for this time except when the drug was withdrawn over PML scare for 9 months as american lawyers and scientists tried to weigh up the PML risk and weather the trial was ‘safe’ enough.
I know on the mountain of safety statistics that have been thrown at me that the JC virus test increases your chance of getting PML. I like millions of others am “POSITIVE”. I have also been on tysabri for 13 years which is another risk factor.
I am wondering if its worth the risk? Maybe have Alemtuzumab (Campath`) and wipe the utterley broken immune system away and build a new one.
I have an appointment with my neuro soon. His standard answer to me raising similar concerns previously is that tysabri is the best choice for me at the moment.