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Moving from natalizumab to Gilenya (Fingolimod)

Good evening, I have been taking natalizumab (tysabri) for the past 5 years, this has worked great causing no relapses in the 5 years. However I have recently been told that because I am JVC positive and have been on the drug for so long I should come off it to stop the chance of getting something else called PML. They have recommended moving on to Gilenya (fingolimod) which has a lesser chance of getting PML, has anyone had any experience with this drug? and if so did how have you found it? Also has anyone else taken this route moving from natalizumab to Gilenya? Any information would be greatly appreciated, Thanks Joe

I’ve been on Gilenya for about eight years, including a year or so on a clinical trial. I haven’t had any major problems with it. There were some mild side effects in the first couple of months but nothing since then. I had one bout of Uhthoff’s Phenomenon a couple of years ago, but no significant relapses. I don’t know anything about natalizumab/Tysabri. I switched to Gilenya from Betaferon. A capsule a day suits me better than injections.