In august 2018 i went along to my MS consultant for my 12/18 month meeting with him. He told me he wanted me to take Tizanidine and Pregabalin as well as Memantine. My wife is adamant that i changed literally over night?. in fact the following month in September we went to south of France. we drove all the way with our 2 road bikes (overnight stop as well). Anyway we got there in the glorious french sunshine!!. 1st ride was a nice ride with incredible views, and some very steep hills. 2nd ride was a very flat encounter with no hills at all following a canal (water cant travel up hill!!)…But within 10 miles i knew my legs were finished (but being a typical man didn’t tell the wife). The saddest thing was, i actually haven’t cycled since!. My wife and MS nurse both said i could have been pushing to hard, and may have caused my own problems?, at the time cycling was my drug, i was riding 200 miles week in week out. currently the only excises i get is walking dog round park when i feel i have it in me?..My legs have never been the same since. my wife reckons i should stop above drugs for 3/6 months to see if any benefits?..
my step daughters friend who knows a bit about drugs thinks the above tablets could or would make me fill like a zombie?..
My current DMD is Tecfidera for 5 years, and Copaxone & Betaferon before that.