Hi, can anyone who has switched medicines give me advice. I’ve been on plegridy for 2.5 years now and I hate it. When I take it it completely wipes me out and I can barely manage anything for a number of days and it’s really getting me down now. In its defence it has been working and I’ve not had any changes in my mri scans for 2 years now which is great. Has anyone switched from plegridy to another dmd that has less side effects or are they all pretty much the same? Thanks
ask your neuro if you can switch and what your options are.
I have only been on 2 DMDs in the 12 years since diagnosis.
Copaxone - an easy one to start with but got nasty injection site reactions.
Tecfidera - an even easier one, 2 tablets a day. side effects were upset tum at first but this soon settled down
(I recommend Omeprazole i this problem continues)
Have a look at https://www.mstrust.org.uk/about-ms/ms-treatments/ms-decisions-aid All the available DMDs are detailed there. Generally the beta interferons have similar side effects to Plegridy, but Copaxone/Brabio doesn’t give you the same flu type side effects. The easiest drug to switch to (ie that you’ll get no problem) is Tecfidera. Oral drug, most common side effects are an upset stomach to begin with (as Carole explained).
But there are others, talk to your MS nurse (assuming you have one), or contact your neurologist and ask for their opinion.
Sue
I take Tecfidera for RRMS and thankfully for me it keeps my MS in remission. Another side effect I get with it is hot flushes which can be embarrassing for menfolk in particular. Regards
I take Tecfidera. No side effects at all. MRI’s all good too.
Good luck.