Hi everyone!
Still waiting to be diagnosed with something (possibly MS).
One of my first cousins was diagnosed with Crohn’s Disease, but this was years ago.
We are caucasian, and we have fathers who are brothers, and mothers who are sisters. (confused??)
Have just found there is a familial connection between these conditions.
Can anyone tell me more??? Thanks!
I have MS and my son was dx’d with Crohn’s two years ago - aged 14! Teresa xx
Sorry this answer is a bit vague (too lazy/tired to research sources right now), but I believe there is some evidence that Crohn’s and MS may have certain biological mechanisms in common, and also that some treatments for Crohn’s also show promise for MS.
I have both Crohn’s and MS in the family, but quite distant relatives in each case, and not both on the same side of the family.
The MS is on my father’s side (one of his aunts), but the Crohn’s on my mother’s (her first cousin died of it - which is rare today, and I think was quite rare even then, but he must have been very unlucky).
Although MS is not regarded as hereditary, I’d always assumed a genetic disposing factor came from my father’s side, but knowing about the Crohn’s in my mother’s family, I wonder now if I got a raw deal from both sides.
There is familial clustering with certain other diseases, too, including Type 1 Diabetes, and Hodgkin’s lymphoma. It’s postulated that all these diseases share certain underlying auto-immune features in common, but the exact link is not yet understood.
Tina
Ditto Tina. Too tired to look further right now and brain not functioning at full capacity (sorry), but there is some sort of recognised link between Crohn’s and MS. I do know that people with Crohn’s are more at risk of developing MS.
My daughter has Crohn’s. I have MS.
Karen x
Hey, Thanks Everyone!!
We still don’t know which side of the family, Maternal or Paternal, this all stems from
but myself and my cousin have both drawn the short straw. Though, fortunately, he &
I only have the one condition each. It’s been really interesting reading your responses.
Thanks once again!!
ali
I’ve never heard of there being a link but am really intrigued as my mum died of crohns and now Im being investigated for ms. If anyone does know anything more about it i would love to know. Thanks
My daughter was diagnosed with Crohns at age 19 that was in 1991, I was diagnosed with MS in 2008. My sister also has MS. I am very interested in any possible links too. Pat
Hi - I read something recently on the net saying that one particular drug can treat both Crohn’s Disease and Multiple Sclerosis equally well. Crohn’s Disease & MS both have a familial gene, meaning that where one case arises within a family, there is every chance that another may just occur - the chances are higher of this happening in a family with already a case, than a case occurring in a family with no known cases. Both Crohn’s andMS are ‘auto-immune disorders’, but with very different symptoms, which kind of makes me believe that basically there must be a ‘weak’ gene within the family, whereby either Crohn’s or MS can take hold. It comes as no surprise that both of these conditons occur within a amily, as they seem to be almost mix-and-match conditions. But rarely, they do occur in one person alone - but it does happen. I may be not be medically trained, but i can definitely spot a link here!! I must mention my cousins Crohn’s to my neurologist.
Hi - I read something recently on the internet saying that one particular drug can treat both Crohn’s Disease and Multiple Sclerosis equally well. I believe Crohn’s Disease and MS both a familial gene, meaning that where one case arises within a family, there is every chance that another case may occur - the chances are higher of this happening within a family with already a case, than a case occurring within a family without any known cases. Both Crohn’s and MS are ‘auto-immune disorders’ (with very different symptoms), which kind of makes me believe that basically there must be a ‘weak’ gene within the family, whereby either Crohn’s or MS can take hold. It comes as no surprise that both of these conditions occur within a family, as they seem to be almost mix-and-match conditions - either one, or possibly both can occur in the same family, but to have both conditons are rarer, but none-the-less possible. I may not be medically trained, but I can certainly spot a link here!! Imust mention my cousins Crohn’s Disease to my neurologist next time.
Hi I have had MS since 2002 and have been very fortunate until last couple of years. I have been diagnosed with Chrohns for past two years. Has anyone heard of people having both?
I am starting on Methothexrate for Chrohns but still nothing for MS as been quite stable untiil last summer when I had a bad attack of vertigo. No sure what is causing symptoms now.
Any advice would be really appreciated.
Thank you.
I have suspected oral crohns and just haven’t had the energy to go for the lip biopsy to get it definitely dx’d, but I’ve been told it is almost certain (oral granulomatosis to give it its official name) I have a history of gut problems passed off by GPs as IBS, but I wonder now.
Anyway, if anyone remembers the name of the drug that has worked for both MS and Crohns, please let me know!