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Tysabri and swollen ankles

Hi I had my second infusion of Tysabri on Monday. Last week my ankles and feet started to get a bit puffy but I never really took that much notice and thought I was just getting fat due to being less active. This morning they have swollen up to the point that it it’s difficult to get my feet in the trainers that I usually wear. I know swellings like this are due to water retention but I am on medication to control excess water because of incontinence. Could it be a side-effect of Tysabri? I’m not really sure what to do.

Hi I’ve been taking Tysabri for nearly a year. I’ve not heard of that side effect. I would ring your MS nurse and speak to them about it.

I have been on Tysabri over 3 years and haven’t come across this before. I would do as Eski suggests and ring your MS Nurse. In the meantime lie or sit with your feet up. Liz