Nicotine Immue Suppression

Last time I posted this question (not long ago) I think I was vastly misinterpreted. So this time I will lead with the question and not personal lead-up. Nicotine is a known immune suppressant. But has anyone become aware of studies of nicotine, the organic compound of Hydrogen, Carbon and Nitrogen, as a potential drug base to help regulate the immune system? I do not suggest anyone takes up smoking. However, I do suggest people remember that:

  • Rat poison is given in controlled doses to treat heart patients
  • Cannabis has been authorised as a drug base for MS (Sativex).
  • Arsenic is used as Arsenic Trioxide to treat certain blood cancers [; ironically it also occurs in cigarettes but not nicotine].
  • Cyanide is used in emergencies to rapidly decrease blood pressure [and is also ironically found in cigarettes but not nicotine].

Often what begins as a poison and is much maligned as such may contain potential benefits from nature that we now, in our media-driven world, refuse to even consider because of bad press. I am talking about the organic nicotine and not smoking as having potential positive impact. It is produced in vast quantities already and is easily obtainable. Have we explored this enough or are we too off-put by the general rejection of anything nicotine related owing to the bad reputation the associated tobacco products bring.

Consider it thus: to be led by popular opinion of late, those of us with MS and in receipt of DLA/PIP are the cause of our economic difficulties. Studies show burnt sausages cause cancer. Red meat causes bowel cancer (and obesity). Sugar causes pancreatic cancer (and obesity and diabetes). So, why do we reject the immuno-suppressant properties of nicotine for development and not reject barbecues and chocolate as acceptable lifestyle elements?

If you are about to respond to this with anti- or indeed pro-smoking comment, please re-read. That is not the question.

I’ve wondered for some time now when / if the positive aspects of nicotine are likely to be studied. I cannot imagine that there are none. It certainly seems that the negative aspects of the drug have completely obscured the potential for any positive attributes to be considered by science. I know so little science that I couldn’t even begin to address this question intelligently but your post seems to me to open the door to sensible consideration.


Nicotine is a nerve painkiller I used to smoke 40 a day before giving up after giving up I had to start on pregabalon

For the nerve pain associated with this

I did find this article - full of medical jargon to be fair - Novel Therapeutic Approach by Nicotine in Experimental Model of Multiple Sclerosis - PMC

Strikes me that if nicotine can be seen to slow the onset of MS in rodent studies, it warrants further exploration, surely.

Funny, I mentioned this to a MS Specialist and he a kinda discounted it - but i have read this before somewhere - I used to smoke and loved it but they (MS specialists) are saying that MSer’s that smoke, tend to show a more rapid disease progression - so nicotine may be the way to go, minus the fags (I still miss them)