# Lipoic acid

**URL:** <https://forum.mssociety.org.uk/t/lipoic-acid/63304>\
**Category:** Everyday living\
**Created:** [15 June 2021 17:11 UTC](https://forum.mssociety.org.uk/t/lipoic-acid/63304 "2021-06-15T17:11:57Z")\
**Posts on this page:** 4\
**Page:** 1

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**Author:** ![Sue84](https://avatars.discourse-cdn.com/v4/letter/s/8baadc/32.png) [@Sue84](https://forum.mssociety.org.uk/u/Sue84)\
**Post date:** [15 June 2021 17:11 UTC](https://forum.mssociety.org.uk/t/lipoic-acid/63304/1 "2021-06-15T17:11:57Z")

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Hi does anyone use Lipoic Acid?

If so how much do you take?

I would appreciate thoughts on this supplement.

Sue

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**Author:** ![Crazy\_Chick](https://avatars.discourse-cdn.com/v4/letter/c/2acd7d/32.png) [@Crazy\_Chick](https://forum.mssociety.org.uk/u/Crazy_Chick)\
**Post date:** [16 June 2021 13:34 UTC](https://forum.mssociety.org.uk/t/lipoic-acid/63304/2 "2021-06-16T13:34:18Z")

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hi it doesnt look like you have had an answer i did a search for it on the forum and found this it might help.

> [@Lipoic Acid anyone?](https://forum.mssociety.org.uk/t/lipoic-acid-anyone/11426):
>
> Lipoic Acid anyone? Hi folks I have been reading (courtesy of Ian Cook’s very helpful msezine) that a fairly large dose (1200mg per day) of Lipoic Acid can help to prevent brain shrinkage in people with SPMS. I don’t seem to be able to see a supplier online who supplies a large enough dose to make any difference, does anyone know of such a supplier could you please let me know, you can message me; if it’s something that will breach forum’s regulations. Thank you for any help you can give. W…

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**Author:** ![Sue84](https://avatars.discourse-cdn.com/v4/letter/s/8baadc/32.png) [@Sue84](https://forum.mssociety.org.uk/u/Sue84)\
**Post date:** [16 June 2021 18:18 UTC](https://forum.mssociety.org.uk/t/lipoic-acid/63304/3 "2021-06-16T18:18:16Z")

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Hi CC Thank you. I have been looking at supplements in desperation to slow decline. I am too old for anything else!

I am waiting for a mri and siponimod was mentioned but I won’t hold my breath as I was turned down for Cladribine two years ago.

Sue

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**Author:** ![Ziola](https://avatars.discourse-cdn.com/v4/letter/z/439d5e/32.png) [@Ziola](https://forum.mssociety.org.uk/u/Ziola)\
**Post date:** [17 June 2021 01:09 UTC](https://forum.mssociety.org.uk/t/lipoic-acid/63304/4 "2021-06-17T01:09:12Z")

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I take alpha lipoic acid. I take 300mg a day. 600mg a day seems to be standard for many of the medical trials with it, though, for a range of conditions, not just ms. Apparently it has a short half-life so perhaps I should be taking 300mg twice a day. It should be taken on an empty stomach.

I do however also take L-carnitine, L-arginine and N-acetylcysteine, as I’m doing an all-round approach, rather than a blitz with just one thing. They all work in slightly different ways, but all are powerful antioxidants, and are neuroprotective and help regeneration of neurons.