# Baclofen having no effect

**URL:** <https://forum.mssociety.org.uk/t/baclofen-having-no-effect/37528>\
**Category:** New diagnosis and before diagnosis\
**Created:** [12 September 2016 07:47 UTC](https://forum.mssociety.org.uk/t/baclofen-having-no-effect/37528 "2016-09-12T07:47:49Z")\
**Posts on this page:** 6\
**Page:** 1

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**Author:** ![Inactive\_User](https://avatars.discourse-cdn.com/v4/letter/i/3e96dc/32.png) [@Inactive\_User](https://forum.mssociety.org.uk/u/Inactive_User)\
**Post date:** [12 September 2016 07:47 UTC](https://forum.mssociety.org.uk/t/baclofen-having-no-effect/37528/1 "2016-09-12T07:47:49Z")

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Hi everyone,

I was prescribed Baclofen 10 days ago and I feel they aren’t working and if anything spasm around ribs are getting worse. I was told to try for few weeks but feel like giving up already! Any advice on this medication would be greatly appreciated I think it’s quite a small dose 5mg \*3 a day.

Thanks

Kellyann

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**Author:** ![Inactive\_User](https://avatars.discourse-cdn.com/v4/letter/i/3e96dc/32.png) [@Inactive\_User](https://forum.mssociety.org.uk/u/Inactive_User)\
**Post date:** [12 September 2016 19:46 UTC](https://forum.mssociety.org.uk/t/baclofen-having-no-effect/37528/2 "2016-09-12T19:46:32Z")

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Hi, I think you need to give the meds a bit longer to work.

Most people are told to find their own optimum dosage with baclofen.

15 mg a day could be too low, but you have to increase it slowly. Has your gp or neuro put you on it?

If it was your gp, then ask for a telephone appointment to discuss increasing the dose.

It is a good drug at reducing spasms and stiffness, but as with all drugs, they affect different folk differently.

A word of warning, if I may, but without wishing to alarm you…take care, as too much may cause weak muscles and this may cause falls.

Pollx

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**Author:** ![Inactive\_User](https://avatars.discourse-cdn.com/v4/letter/i/3e96dc/32.png) [@Inactive\_User](https://forum.mssociety.org.uk/u/Inactive_User)\
**Post date:** [12 September 2016 20:55 UTC](https://forum.mssociety.org.uk/t/baclofen-having-no-effect/37528/3 "2016-09-12T20:55:09Z")

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Hi Poll,

Thanks for your reply. It was g.p. that put me on them will give them another week and then give doc a call. Neuro did warn me about muscle weakness but I don’t see that happening anytime soon my legs are solid at the moment but thank you for advice I really do appreciate it. I’ve tried to stay away from drugs but spasms were just excruciating don’t know what to do for best.

Thanks

Kellyann

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**Author:** ![DAVIDD](https://avatars.discourse-cdn.com/v4/letter/d/ecc23a/32.png) [@DAVIDD](https://forum.mssociety.org.uk/u/DAVIDD)\
**Post date:** [17 September 2016 13:42 UTC](https://forum.mssociety.org.uk/t/baclofen-having-no-effect/37528/4 "2016-09-17T13:42:17Z")

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hi kellyann

I took baclofen to begin with when first dx’d , at that time I found my legs felt like two limp sticks of celery, I put it down to MS , it was in fact the baclofen itself that was causing them to be more limp than the MS had caused. I changed to tizanidine and felt a difference for the better immediately. What I found was that where baclofen made all my muscles feel limp the tizanidine seemed to be more targeted . and I was getting relief from spasticity but at same time it wasn’t causing the limpness in my legs. Tizanidine is worth checking out, I know that what works for one might not work for other but still worth checking.

david

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**Author:** ![catwomanCarole58](https://avatars.discourse-cdn.com/v4/letter/c/e95f7d/32.png) [@catwomanCarole58](https://forum.mssociety.org.uk/u/catwomanCarole58)\
**Post date:** [17 September 2016 14:36 UTC](https://forum.mssociety.org.uk/t/baclofen-having-no-effect/37528/5 "2016-09-17T14:36:17Z")

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baclofen sent me to sleep!

it was like i’d had an anaesthetic.

getting down stairs was scary so i stopped taking it.

carole x

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**Author:** ![Inactive\_User](https://avatars.discourse-cdn.com/v4/letter/i/3e96dc/32.png) [@Inactive\_User](https://forum.mssociety.org.uk/u/Inactive_User)\
**Post date:** [17 September 2016 16:03 UTC](https://forum.mssociety.org.uk/t/baclofen-having-no-effect/37528/6 "2016-09-17T16:03:20Z")

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Hi

Thanks for replies. I’ve actually stopped taking them a couple of days ago as they weren’t helping at all and felt scared to up dose after reading reviews about them. I’ve got neuro appt in 4 weeks and I’m going to ask if there’s anything he would suggest. I take a lot of magnesium, stretching etc. but feel nothing’s working on tin man legs haha x
